South Dakota has 58,052 companies. The cities with the most companies are Sioux Falls, Rapid City, Aberdeen, Watertown, Yankton. The most popular type of business in South Dakota is Uncategorized, followed by Churches, Agriculture and Forestry, Contractors, Nurses.
- Aberdeen
- Alcester
- Alexandria
- Alpena
- Andover
- Arlington
- Armour
- Artesian
- Astoria
- Aurora
- Avon
- Baltic
- Bath
- Belle Fourche
- Beresford
- Big Stone City
- Bison
- Black Hawk
- Blunt
- Bonesteel
- Bowdle
- Box Elder
- Bradley
- Brandon
- Brandt
- Bridgewater
- Bristol
- Britton
- Brookings
- Bruce
- Bryant
- Buffalo
- Burbank
- Burke
- Canistota
- Canova
- Canton
- Carthage
- Castlewood
- Cavour
- Centerville
- Central City
- Chamberlain
- Chancellor
- Chester
- Claire City
- Claremont
- Clark
- Clear Lake
- Colman
- Colome
- Colton
- Columbia
- Conde
- Corona
- Corsica
- Cresbard
- Crooks
- Custer
- Dakota Dunes
- Dallas
- Davis
- De Smet
- Deadwood
- Dell Rapids
- Delmont
- Dimock
- Doland
- Dupree
- Eagle Butte
- Eden
- Edgemont
- Egan
- Elk Point
- Elkton
- Ellsworth Afb
- Emery
- Estelline
- Ethan
- Eureka
- Fairfax
- Faith
- Faulkton
- Flandreau
- Florence
- Forestburg
- Fort Meade
- Fort Pierre
- Frankfort
- Frederick
- Freeman
- Garretson
- Gary
- Gayville
- Geddes
- Gettysburg
- Glenham
- Goodwin
- Gregory
- Grenville
- Groton
- Harrisburg
- Harrison
- Harrold
- Hartford
- Hayti
- Hazel
- Hecla
- Henry
- Hermosa
- Herreid
- Herrick
- Hetland
- Highmore
- Hill City
- Hitchcock
- Hosmer
- Hot Springs
- Houghton
- Hoven
- Howard
- Hudson
- Humboldt
- Hurley
- Huron
- Interior
- Ipswich
- Irene
- Iroquois
- Isabel
- Java
- Jefferson
- Kadoka
- Kennebec
- Keystone
- Kimball
- Lake Andes
- Lake Norden
- Lake Preston
- Langford
- Lead
- Lemmon
- Lennox
- Leola
- Lesterville
- Letcher
- Lower Brule
- Madison
- Mansfield
- Marion
- Martin
- Mc Intosh
- Mc Laughlin
- Meadow
- Meckling
- Mellette
- Menno
- Midland
- Milbank
- Miller
- Mina
- Mission
- Mission Hill
- Mitchell
- Mobridge
- Montrose
- Morristown
- Mound City
- Mount Vernon
- Murdo
- New Effington
- New Underwood
- Newell
- Nisland
- North Sioux City
- Northville
- Oacoma
- Oelrichs
- Oldham
- Olivet
- Onaka
- Onida
- Orient
- Parker
- Parkston
- Philip
- Piedmont
- Pierpont
- Pierre
- Pine Ridge
- Plankinton
- Platte
- Pollock
- Prairie City
- Presho
- Pukwana
- Ramona
- Rapid City
- Redfield
- Ree Heights
- Renner
- Revillo
- Roscoe
- Rosholt
- Roslyn
- Saint Francis
- Saint Onge
- Salem
- Scotland
- Selby
- Seneca
- Sherman
- Sioux Falls
- Sisseton
- South Shore
- Spearfish
- Spencer
- Springfield
- Stickney
- Stockholm
- Stratford
- Sturgis
- Summerset
- Summit
- Tabor
- Tea
- Timber Lake
- Tolstoy
- Toronto
- Tripp
- Tulare
- Turton
- Tyndall
- Union Center
- Utica
- Vale
- Valley Springs
- Veblen
- Vermillion
- Viborg
- Volga
- Volin
- Wagner
- Wakonda
- Wall
- Warner
- Watertown
- Waubay
- Webster
- Wentworth
- Wessington
- Wessington Springs
- White
- White Lake
- White River
- Whitewood
- Willow Lake
- Wilmot
- Winfred
- Winner
- Witten
- Wolsey
- Woonsocket
- Worthing
- Yale
- Yankton